Document Type : Research Paper


1 Associate Professor, Department of Physical Education, Payame Noor University, Tehran, Iran

2 MSc, Department of Physical Education, Payame Noor University, Tehran, Iran


The aim of this study was to investigate the effect of Spark activity on growth hormone level and motor skills in 4-7-year-old boys with attention deficit / hyperactivity disorder. In this quasi-experiments study, 20 children with attention deficit/hyperactivity disorder (ADHD) were selected by multi-stage cluster sampling method from kindergartens of districts 2 and 5 of Tehran city. Then, subjects were randomly assigned to two groups: control (n=10) and experimental (n=10). The experimental group received Spark activity for 24 sessions and the control group performed their daily activities during this period. Blood samples were collected from the subjects before and after the intervention to measure the amount of growth hormone. Bruininks-Oseretsky test was used to assess motor skills. Data were analyzed using paired t test and covariance at a significance level of P<0.05. There was a significant difference between experimental and control groups in the scores of fine and gross motor skills, which were higher in the experimental group than in the control group (P=0.001). There were no significant differences in growth hormone level between the two groups (P=0.399). Based on these results, it can be concluded that one period of Spark activity can play an effective role in improving motor skills and this improvement is not associated with the level of growth hormone.


1.Alizadeh H. Theoretical explanation of the disorder, attention deficit /hyperactivity over pattern of behavioral inhibition and self-control nature. Res Domain Except Child. 2005;17:323-43.[In Persian]
2.Kluwer W. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM–5).Indian journal of psychiatry. Indian journal of psychiatry. 2013;55(3):220-3.
3.Biederman J, Faraone SV. Attention-deficit hyperactivity disorder. Lancet. 2005;366 (9481):237-48.
4.Azadbakht L, Esmaillzadeh A. dietary patterns and attention deficit hyperactivity disorder among Iranian children. Nutrition. 2012;28(3):242-9.
5.Sahin S, Yuce M, Alacam H, Karabekiroglu K, Say GN, Salıs O. Effect of methylphenidate treatment on appetite and levels of leptin, ghrelin, adiponectin, and brain-derived neurotrophic factor in children and adolescents with attention deficit and hyperactivity disorder. Int J Psychiatry Clin Pract. 2014;18(4):280-7.
6.Yan L, Zhang J, Yuan Y, Cortese S. Effects of neurofeedback versus methylphenidate for the treatment of attention-deficit/hyperactivity disorder protocol for a systematic review and meta-analysis of head-to-head trials. Medicine (Baltimore). 2018;97(39):e12623.
7.Alexander L, Farrelly N. Attending to adult ADHD: a review of the neurobiology behind adult ADHD. Ir J Psychol Med. 2018;35(3):237-44.
8.Sharma A, Couture J. A review of the pathophysiology, etiology, and treatment of attention-deficit hyperactivity disorder (ADHD). . Ann Pharmacother. 2014;48(2):209-25.
9.Tarver J, Daley D, Sayal K. Attention-deficit hyperactivity disorder (ADHD): an updated review of the essential facts. Child Care Health Dev. 2014;40(6):762-74.
10.Rosa Neto F, Goulardins JB, Rigoli D, Piek JP, Oliveira JA. Motor development of children with attention deficit hyperactivity disorder. Braz J Psychiatr. 2015;37(3):228-34.
11.Pan CY, Chang YK, Tsai CL, Chu CH, Cheng YW, Sung MC. Effects of Physical Activity Intervention on Motor Proficiency and Physical Fitness in Children with ADHD: An Exploratory Study. J Atten Disord. 2017;21(9):783-95.
12.Cho H, Ji S, Chung S, Kim M, Joung YS. Motor function in school-aged children with attention-deficit/hyperactivity disorder in Korea. Psychiatry Investig. 2014;11(3):223-7.
13.Webb EA, O'Reilly MA, Clayden JD, Seunarine KK, Chong WK, Dale N, et al. Effect of growth hormone deficiency on brain structure, motor function and cognition. Brain Behav Evol. 2012;135(Pt 1):216-27.
14.Reus L, Pillen S, Pelzer BJ, van Alfen-van der Velden JA, Hokken-Koelega AC, Zwarts M, et al. Growth hormone therapy, muscle thickness, and motor development in Prader-Willi syndrome: an RCT. Pediatrics. 2014;134(6):e1619-e27.
15.Yasuhara A, Yoshida Y. Beneficial effect of growth hormone on severe delay in motor development in a child with Down syndrome. Clin Pediatr Endocrinol. 2001;10(2):137-40.
16.Hatzinger M, Brand S, Perren S, von Wyl A, von Klitzing K, Holsboer-Trachsler E. Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children: importance of gender and associations with behavioral/emotional difficulties. J Psychiatr Res. 2007;41(10):861-70.
17.Galvez-Contreras AY, Campos-Ordonez T, Gonzalez-Castaneda RE, Gonzalez-Perez O. Alterations of Growth Factors in Autism and Attention-Deficit/Hyperactivity Disorder. Front Psychiatry. 2017;8:126.
18.Torabi F, Ebrahim R, Hemayattalab R, Ramezankhani A. Effectiveness of High-Intensity Interval Exercise on Serum Dopamine Level and Improvement of Perceptual-Motor Skills in Male Students with Hyperactivity/Attention Deficit Disorder. Horizon Med Sci. 2017;23(1):35-9. [In Persian]
19.Johnson MH, Gliga T, Jones E, Charman T. Annual Research Review: Infant development, autism, and ADHD – early pathways to emerging disorders. J Child Psychol Psychiatry. 2015;3:228-24.
20.Aron AR, Robbins TW, Poldrack RA. Inhibition and the right inferior frontal cortex: one decade on. Trends Cogn Sci. 2014;18:177-85.
21.Torabi F, Ebrahim R, Hemayattalab R, Ramezankhani A. Effect of 6 weeks high intensity interval training on dopamine levels and improvement of perceptual motor skills in adolescent girls with attention deficit hyperactivity disorder. RJMS. 2016;23(148):106-14.[In Persian]
22.Afghan M, Gaeini AA, Razzaghiazar M, Mojarrad M, Shabani M, Hosseinpanah F. The effect of a physical activity program on IGF-I and IGFBP-3 levels in short stature children. Research in Medicine. 2014;38(1):47-52.[In Persian]
23.Faal Moganloo H, Hosseini F, Mikaili Manee F. Effect of Spark Motor Program on the development of gross motor skills in intellectually disabled educable boys. J Birjand Univ Med Sci. 2013;20(3):262-70.[In Persian]
24.Friedrich RR, Schuch I, Wagner MB. Effect of interventions on the body mass index of school-age students. Rev Saude Publica. 2012;46(3):551-60.
25.Boisseau N, Delamarche P. Metabolic and hormonal responses to exercise in children and adolescents. Sports Med. 2000;30(6):405-22.
26.Bagheri MH, Bambaeichi F, Esfarjani FR, Sattar M. The effect of 8 weeks of water training on growth hormone and insulin-like growth factor in children. Journal of sport biosciences. 2013;4(14):21-36.
27.Amirsasan R, Sari-Saraf V, Pourgholi T, Armanfar M. Comparing the effects of combined endurance-resistance training versus resistance-endurance on growth hormone and insulin-like growth factor-I in non-athlete prepubertal girls. Feyz. 2015;19(3): 214-22. [In Persian]
28.Mahon AD, Stephens BR, Cole AS. Exercise responses in boys with attention deficit/hyperactivity disorder: effects of stimulant medication. J Atten Disord. 2008;12(2):170-6.
29.Maddigan B, Hodgson P, Heath S, Dick B, St John K, McWilliam-Burton T, et al. The effects of massage therapy & exercise therapy on children/adolescents with attention deficit hyperactivity disorder. Can Child Adolesc Psychiatr Rev. 2003;12(2):40-3.
30.Cerillo-Urbina AJ, Garcia-Hermoso A, Sanchez-Lopez M, Pardo-Guijarro MJ, Santos Gomez JL, Martinez-Vizcaino V. The effects of physical exercise in children with attention–deficit/hyperactivity disorder: a systematic review and meta-analysis of randomized control trials. Child Care Health Dev. 2015;41(6):779-88.
31.Sami S, Karimyani N, Sayed Ebrahimi S, Hakimi M. Comparing the Motor Proficiency in Children with Attention-Deficit Hyperactivity Disorder (ADHD). Journal of Ilam University of Medical Sciences. 2014;21:223-36. [In Persian]