Tahmineh Karbalaee Sadeghi; Morteza Taheri; Khadijeh Irandoust
Abstract
Introduction: Colon cancer or colorectal cancer is the growth of cancerous masses in the colon. According to research evidence, the use of antioxidants and regular exercise are the best ways to prevent and treat many diseases. This study aimed to investigate the effect of eight weeks of intermittent ...
Read More
Introduction: Colon cancer or colorectal cancer is the growth of cancerous masses in the colon. According to research evidence, the use of antioxidants and regular exercise are the best ways to prevent and treat many diseases. This study aimed to investigate the effect of eight weeks of intermittent exercise and Quercetin consumption on the brain-derived neurogenic factor (BDNF) and cyclic-adenosine monophosphate responsive element-binding protein (CREB) in the brain hippocampus of rats with colon cancer which has many influences on cognitive functions.Methods: The subjects of this study included 50 male Wistar rats (weight: 250±30 grams, age: 12 weeks) which were homogenized by weight and were randomly divided into five Healthy Control, Cancer Control, Cancer + Quercetin supplement, Cancer + Intermittent exercise, Cancer + Quercetin supplement + Intermittent exercise groups (10 rats in each group). BDNF and CREB measurements were performed in the rats’ hippocampus according to the ELISA standards and method. SPSS software was used for data analysis.Results: The results showed that eight weeks of intermittent exercises had a significant effect on the mean score of BDNF (p = 0.047) and CREB (p = 0.032) in rats’ hippocampus with colon cancer. Eight weeks of Quercetin supplementation had no significant effect on the mean BDNF score (p = 0.792) and the mean CREB score (p = 0.363) in rats’ hippocampus with colon cancer Conclusion: In general, the findings showed that intermittent exercise and Quercetin supplementation improve BDNF and CREB in the hippocampus of rats with colon cancer.
Shahrian Eshaghi; Morteza Taheri; Khadijeh Irandoust
Abstract
The purpose of this study was to investigate the effect of a course of aerobic exercise and vitamin D supplementation on the psychomotor function of elderly women with sleep disorders. Based on this, 42 people were selected in an accessible and targeted manner with an age range of 60-70 years. They all ...
Read More
The purpose of this study was to investigate the effect of a course of aerobic exercise and vitamin D supplementation on the psychomotor function of elderly women with sleep disorders. Based on this, 42 people were selected in an accessible and targeted manner with an age range of 60-70 years. They all suffered from insomnia. Subjects were randomly divided into four groups: aerobic exercise, aerobic exercise-vitamin D supplement, vitamin D supplement and control group. Vitamin D intake in both groups was taken as 2000 units daily. The Physical Activity Readiness Diagnostic Questionnaire (PARQ) was used to know the level of physical fitness of the subjects and the Gibson 24-hour diet recall questionnaire the day before the pre-test and post-test. The Pittsburgh Sleep Quality Scale was used to extract the sleep profile. COG psychomotor test was also used to assess cognitive and mental components and information processing. The results showed that the aerobic, supplement and aerobic-supplement groups had a significant improvement in selective attention and reaction time. Also, the aerobic-supplement group had a significant improvement in selective attention and reaction time compared to the aerobic group and the supplement group. Aerobic exercise along with vitamin D supplementation seems to improve the motor and motor function of older women. Therefore, vitamin D supplementation and aerobic exercise in interaction are recommended for older women.
khadijeh Irandoust; Morteza Taheri; Ali Seghatoleslami
Abstract
The purpose of this study is to investigate the effect of physical activity onmemory and dynamic balance of elder people. Subjects (n=15) were selected asvolunteers. The intervention was performed in an eighteen session period, threetimes a week (each session, 45 minutes). Yoga training was performed ...
Read More
The purpose of this study is to investigate the effect of physical activity onmemory and dynamic balance of elder people. Subjects (n=15) were selected asvolunteers. The intervention was performed in an eighteen session period, threetimes a week (each session, 45 minutes). Yoga training was performed for mentalrelaxation. Wexler test was performed for memory evaluation. Seat up test wasused to test the dynamic balance. The results suggested that water-based exercisesand Yoga protocol have had a positive significant effect on memory (p=0.03) anddynamic balance. It was concluded that a selected physical activity program,especially water-based exercises has less potential for making people injured.