Elham Azizi; Esmail Nasiri; Maryam Khalesi
Abstract
Introduction: Sports activities can protect the brain and improve its function. However, the lack of time is one of the primary reasons for not participating in the recommended amount of sports activities. Therefore, the present study aimed to investigate the effects of sprint interval training (SIT) ...
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Introduction: Sports activities can protect the brain and improve its function. However, the lack of time is one of the primary reasons for not participating in the recommended amount of sports activities. Therefore, the present study aimed to investigate the effects of sprint interval training (SIT) on hippocampal nerve growth factor (NGF) levels, learning, and spatial memory in adult male rats.Methods: For this, 16 male Wistar rats were divided into two equal groups (control and SIT). The SIT protocol consisted of eight weeks of running on the treadmill (three sessions per week, 4-9 repetitions of 10 seconds sprints, and 1 min rest between repetitions). At the end of the eighth week, the rats’ cognitive performance was evaluated using the shuttle box and Y-maze avoidance tests. Finally, rats were anesthetized and the hippocampus was removed and NGF levels were measured.Results: The findings showed that in the SIT group, the hippocampal NGF levels were significantly higher than the control group (p=0.001). Moreover, rats in the SIT group had better performance in the shuttle box and Y-maze avoidance tests than the control group, but the difference between groups was not statistically significant (p>0.05).Conclusion: Based on the findings of the present study, it seems that SIT (with 10 seconds repetitions) can increase the hippocampal NGF levels, though, to improve our knowledge about its effect on cognitive performance, more studies are needed
Mohammad Hossein Zamani; Hamidreza Taheri Torbati; Aireza Saberi Kakhki; Majid Ghoshoni
Abstract
The purpose of this study was to investigate the effect of visual illusion on the learning of throwing skills in autism children. The research method was semi-experimental with repeated design and retention test. The statistical sample of this study was 33 children of 10 years old who were selected available ...
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The purpose of this study was to investigate the effect of visual illusion on the learning of throwing skills in autism children. The research method was semi-experimental with repeated design and retention test. The statistical sample of this study was 33 children of 10 years old who were selected available and were divided into three groups randomly: larger circle perceptions, smaller circle perceptions and control group. The tool used in this study was the Ebbinghaus illusion displayed on the ground and the beanbags for throwing from down to shoulder to goal. At first, the participants performed ten trials at the pre-test phase. Then, in the acquisition phase, 20 blocks completed 10 trials. 48 hours after the last session of the acquisition, a retention test was performed in 10 trials of the participant. To analyze the data, mixed analysis of variance analysis with repeated measures, one way analysis of variance and Tukey's follow-up were used. The results of this study showed that there was a significant difference between the groups both in the acquisition phase and in the retention phase between the groups, which this difference was in favor of the larger circle's perception group. Overall, the results of this study showed that a simple perceptual manipulation can increase motor learning in children with autism. Therefore, it is suggested to educators and sports practitioners to use this variable to improve their performance and improve their training sessions.
Elahe Siavashi; Ali Heyrani; Ehsan Zareian
Abstract
The aim of this study was to investigate The effect of skill level matching in cooperative dyadic interaction on learning of forehand table tennis skills in adolescent girls. Participants were selected convenience sampling form from 24 junior high school girls in Nahavand city and were randomly divided ...
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The aim of this study was to investigate The effect of skill level matching in cooperative dyadic interaction on learning of forehand table tennis skills in adolescent girls. Participants were selected convenience sampling form from 24 junior high school girls in Nahavand city and were randomly divided into two groups of Novice-Novice and Novice-Expert. Both groups performed five sessions of participatory dyad training with their respective arrangement (novice- novice, novice- expert) that each session consisted of 20 sets of 3-minute with a 1-minute rest time between sets. Using table tennis forehand shot accuracy test, the motor performance was measured in the pre-test, post-test, retention and transfer stages (Merely forehand performance with increasing throwing speed of ball thrower). The results showed that both Novice-Novice and Novice-Expert groups showed significant progress learning of forehand table tennis skills; Also, the Novice-Expert performed better in the post-test, retention and transfer stages than the Novice-Novice group. Therefore, Novice-Expert arrangement than Novice-Novice during participatory dyad training facilitates learning forehand table tennis skill.It revealed that novice-expert arrangement is more efficient in comparison to novice-novice arrangement as the former enjoys the benefits of using the optimal observational pattern (seeing a expert person), and offeres various challenges and strategies for the novice partner as a result of exercising with an expert partner. To conclude, novice-expert dyad practice promotes the speed of learning among table tennis learners.
Souri Heidari; Abdolrahman Khezry; Mahmoud Sheikh
Abstract
The aim of this study was to compare the transfer of proactive learning between front and back crawl swimming skills in female beginners. 60 students who had registered in elementary swimming course were selected and assigned to four groups (two experimental and two control groups). Experimental groups ...
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The aim of this study was to compare the transfer of proactive learning between front and back crawl swimming skills in female beginners. 60 students who had registered in elementary swimming course were selected and assigned to four groups (two experimental and two control groups). Experimental groups learned a primary task (front or back crawl swimming) for 10 sessions and then learned the secondary task (front or back crawl swimming; contrary to the primary task). The participants of control groups participates only in secondary task. The results showed that amount of proactive transfer from front crawl to back crawl was 3.06% which was not statistically significant (P=0.977) while the amount of transfer from back crawl to front crawl was 13.45% which was statistically significant (P=0.013). On the other hand, to compare the amount of transfer of these two types of swimming, the results of U Mann Whitney test showed that the amount of proactive transfer of back crawl to front crawl was significantly higher than the amount of transfer of front crawl to back crawl (P=0.001). Therefore, these results support the sequence of back-front crawl swimming instruction in beginners.
Mohammad Hossein Zamani; Ayoub Hashemi; Rasool Abedanzadeh
Abstract
The aim of this study was to investigate the effect of feed forward augmented information in model observation on learning mini basketball free throw skill in children. For this purpose, 45 children (10 years old) were selected as the sample by convenience sampling method and were divided into three ...
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The aim of this study was to investigate the effect of feed forward augmented information in model observation on learning mini basketball free throw skill in children. For this purpose, 45 children (10 years old) were selected as the sample by convenience sampling method and were divided into three groups: feed forward augmented information + observation, observation + KR feedback, and control (C). The research method was semi-experimental and research design was pretest-posttest and retention test. The task used in this study was mini basketball free throw skill. Firstly, the participants performed 15 trials in the pretest. The acquisition phase consisted of 6 blocks of 15 trials of observation followed by physical training. The retention test was performed 48 hours after the last training block in 15 trials. The data were analyzed by mixed analysis of variance, between-group analysis of variance and Tukey post hoc test. The results showed that both at the acquisition and retention phases, feed forward augmented information + observation group who were knowledgeable about the quality of the model prior to the observation showed better performance than the other two groups (P<0.05). Generally, these results showed that knowledge of the model performance before observation can make learning of a throwing task more significant than the time when they were knowledgeable after the observation. Therefore, it is suggested that feed forward augmented information on the quality of the model before observation should be used to improve the performance of the subjects.
Zahra Soori; Ali Heyrani; Rahman Souri
Abstract
The role of the training is to improve the symptoms of Parkinson's disease. The purpose of this study was to compare the effects of exercise intensity on learning, spatial memory and anxiety behaviors in rat with impair . In this study, 24 male rats were randomly divided into 5 healthy control groups, ...
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The role of the training is to improve the symptoms of Parkinson's disease. The purpose of this study was to compare the effects of exercise intensity on learning, spatial memory and anxiety behaviors in rat with impair . In this study, 24 male rats were randomly divided into 5 healthy control groups, Parkinson's control, Parkinson's (low, moderate, and high intensity) exercises. The creation of the Parkinson's Model was injected intra-brain-6-hydroxydopamine. To assess learning and spatial memory, Morris water maze test and Counting Counting were used as an indicator of anxiety behavior. Data analysis was done by one-way ANOVA at a significant level (P <0.05). Injection of 6-hydroxydopamine increased the duration of the platform and destroyed spatial memory (P <0.05), Although all three types of space memory training decreased significantly in Parkinson's rats significantly (P <0.05), high intensity exercise showed the greatest effect on learning and spatial memory (0.05). (P <0.05), there was a significant difference between the high and low intensity training groups (P <0.05). This difference was not significant between the moderate and low intensity groups in most of the variables (P <0.05). Different intensities, especially high intensity, improve the parameters of spatial memory
Nastaran Naderirad; Ali Akbar Jaberi Moghadam; Shahzad Tahmasebi Boroujeni
Abstract
Postural control is one of the important abilities in daily life and sport activities of human beings and the importance of focus of attention is always discussed in this issue. In this regard, the aim of the present study was to investigate the effect of the instructions of focus of attention ...
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Postural control is one of the important abilities in daily life and sport activities of human beings and the importance of focus of attention is always discussed in this issue. In this regard, the aim of the present study was to investigate the effect of the instructions of focus of attention of supra-postural task on performance and learning of postural control in girls aged between 9 and 12. 45 female students in an elementary school in Malayer city participated in this study and were randomly divided into 3 groups: external attention, internal attention and control by drawing of lots. The participants were asked to maintain their postural control by instructions on supra-postural task. Instructions included focus of attention on the bar they held horizontally (external focus), on their hands (internal focus) and no instructions (control). The results of analysis of variance with repeated measures showed that learning process in external focus group was significant compared with the internal focus (P=0.049) and control (P=0.005) groups. However, no significant differences were found in learning between internal focus and control groups (P=0.345). It can be concluded that external attention instruction on supra-postural task led to better postural control than internal attention instruction.
Tayebe Taherpouri; Parvaneh Shafineya; Mahdi Zarghami
Abstract
Various researches know lateral preference of eye and hand pattern as one of the important factors of performing sports skills. This study aimed at investigating the effect of lateral preference of eye and hand pattern on learning basketball free throw skill. From 3000 female students of Shahid ...
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Various researches know lateral preference of eye and hand pattern as one of the important factors of performing sports skills. This study aimed at investigating the effect of lateral preference of eye and hand pattern on learning basketball free throw skill. From 3000 female students of Shahid Chamran University of Ahvaz, 60 subjects (age range 19-22 yr) were selected purposively as the sample using a researcher-made questionnaire of individual information and sporting background, Edinburgh Handedness Inventory (Oldfield, 1971) and hole card (Durand and Gold, 1910) and were assigned to two control and experimental groups (each group: 15 unilateral subjects and 15 crossed-lateral subjects). Firstly, pretest of basketball free throw was conducted. Then, practice protocol was performed for 8 weeks (24 sessions, 3 sessions a week). During this period, 6 posttests were administered to determine learning stages and one week after the last posttest, the retention test was conducted. The results showed a significant difference between unilateral and crossed-lateral (experimental group) subjects in the cognitive (sig=0.000) and associative (sig=0.000) stages of the acquisition of basketball free throw and the unilateral subjects had a better performance. Whereas there was no significant difference between unilateral and crossed-lateral subjects in the autonomous (sig=0.105) and retention (sig=0.086) stages. Finally, the results showed a difference in performance between experimental and control groups in favor of experimental group. According to these results, it seems that long practice and autonomous skill in unilateral and crossed-lateral subjects matched their performance and eliminated their differences. Therefore, coaches are recommended to identify talented subjects after a lot of practice in order to not generalize the result of performance to learning.
Ahmadreza Movahedi; Abbas Bahram; Sahar Bordbar
Abstract
The aim of the present study was to investigate the effect of different methods of self-talk (motivational, instructional, and combined) on acquisition and learning of a motor perceptional task (dart) and physical efficacy in female students aged between 13 and 18. 48 female students (mean age 15.46 ...
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The aim of the present study was to investigate the effect of different methods of self-talk (motivational, instructional, and combined) on acquisition and learning of a motor perceptional task (dart) and physical efficacy in female students aged between 13 and 18. 48 female students (mean age 15.46 yr) who were novice at dart throwing voluntarily participated in this study. Participants were divided into 4 groups including motivational self-talk, instructional self-talk, motivational-instructional self-talk and physical practice (12 students in each group) following an initial instructional session and pretest. The intervention included 10 sessions of acquisition, 2 sessions of retention test and one session of transfer test. One-way ANOVA and ANOVA with repeated measures were used to analyze data. Results showed that combined (motivational-instructional) and the instructional self-talk groups improved dart throwing performance in acquisition, immediate and delayed retention sessions in 13-18-year-old students compared with the motivational self-talk and physical exercise groups. Instructional self-talk group showed the best performance in transfer test while the other three groups showed almost similar performances. The results also showed that different interventions had no significant effects on physical self-efficacy of the participants.
Ghoobad Mehrabeyan; Ali Heirani; Mahmoud Gholipoor
Abstract
This study aimed at examining the effect of different focus of attention instructions and cognitive styles on the learning of dart throwing skill. 80 children were randomly selected and divided into four equal groups: a) field independent-external attention, b) field independent-internal attention, c) ...
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This study aimed at examining the effect of different focus of attention instructions and cognitive styles on the learning of dart throwing skill. 80 children were randomly selected and divided into four equal groups: a) field independent-external attention, b) field independent-internal attention, c) field dependent-external attention and d) field independent-internal attention based on their pretest scores (10 trials of dart throwing). Then, in acquisition phase, they practiced 6 blocks of 10 trials of dart throwing task with regard to their focus of attention and cognitive style. Retention test was conducted 24 hours after the acquisition phase similar to pretest. After ensuring data normality by Kolmogorov-Smirnov test, ANOVA 4*6 with repeated measures was conducted on block factor and one-way ANOVA and Bonferroni post hoc test was applied in acquisition and retention phases respectively. Results showed significant differences in scores of all groups in all phases (P<0.05) and those with field independent style had better performance in external focus of attention than internal focus of attention and those with field dependent style had better performance in internal focus of attention than external focus of attention. In other words, cognitive styles must be noted during recruiting the focuses of attention.
Hamide Jahanbakhsh; Parvane Shafienaya; Seyede Nahid Shetab Booshehri
Abstract
Normative feedback is a kind of feedback which involves information about an individual's performance in comparison with other peers unrealistically (positive or negative). The aim of the present study was to determine the effect of normative feedback on throwing aiming task learning in children aged ...
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Normative feedback is a kind of feedback which involves information about an individual's performance in comparison with other peers unrealistically (positive or negative). The aim of the present study was to determine the effect of normative feedback on throwing aiming task learning in children aged between 9 and 11 in Ahvaz city. For this purpose, 90 right-handed children were selected with convenience method as the statistical sample and were divided into three groups (each group 30 subjects) of positive normative feedback, negative normative feedback and control based on their age, height, weight, hand length, arm length and pretest scores. Acquisition phase included 6 blocks of 10 trials. In this phase, all groups received real feedback after each trial and positive and negative normative groups received normative feedback after each block in addition to real feedback. The transfer and retention tests were carried out immediately and after (delayed) the acquisition phase respectively. After checking the data normality and homogeneity of variances, data were analyzed with one-way ANOVA with repeated measures, one-way analysis of variance, and Bonferroni post hoc test (P≤0.05). There were significant differences in all three phases among the three groups and positive normative feedback group showed better performance (P=0.001). The findings showed that positive normative feedback had a facilitating effect on motor learning.
Ayoob Sabaghi; Ali Heirani
Abstract
This study aimed at comparing the effect of self-controlled feedback with 100% frequency on motor skill learning in children. 60 children (11.1±0.86 yr) were selected randomly and based on their pretest results divided into same three groups of 100% feedback, self-controlled and yoked. In the ...
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This study aimed at comparing the effect of self-controlled feedback with 100% frequency on motor skill learning in children. 60 children (11.1±0.86 yr) were selected randomly and based on their pretest results divided into same three groups of 100% feedback, self-controlled and yoked. In the acquisition phase, subjects completed 120 trials. At the end of the second day, subjects performed a 10-trial block as the acquisition test. After 48 hours, retention test was conducted like the acquisition test. MANOVA with repeated measures on the intra-group factor (trial blocks) was recruited in the acquisition phase and one-way ANOVA and LSD post hoc test was used for the retention phase. The results of the acquisition phase showed the significant effect of blocks (P<0.05). The findings of the retention phase showed that 100% feedback and self-controlled feedback groups had better results than the yoked group (P<0.05). Also, in two self-controlled subgroups, the group which received feedback above 50% had better performance. The pattern of these results supported former findings about the effectiveness of feedback in motor learning. In addition, it showed that frequency of feedback had to be high in children during self-controlled feedback.
Nafiseh Afshari; Shahzad Tahmasebi Boroujeni; Naser Naghdi; Rasool Hemayat Talab
Abstract
Increased level of stress has negative effects on cognitive functions. Thus, it is necessary to identify appropriate strategies to prevent cognitive and motor performance decline. The aim of this research was to study the effect of immobilization stress on learning and memory and the protective role ...
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Increased level of stress has negative effects on cognitive functions. Thus, it is necessary to identify appropriate strategies to prevent cognitive and motor performance decline. The aim of this research was to study the effect of immobilization stress on learning and memory and the protective role of physical activity in them. From male Albino-Wistar rats of Pastor Institute, 32 rats were randomly divided into four groups. According to the type of the groups, rats were exposed to stress interventions including immobilization (two hours per day for 21 days), moderate running (30 minutes per day for 21 days), combination of stress interventions and running and also without any interventions. In order to determine the effectiveness of stress, animal weights were measured in two phases: before the protocol and after the tests. Morris Water Maze in several steps (four days for the acquisition phase, the fifth day for Probe test, three days for resting and the ninth day for recall test) was used for learning and testing of rats. ANOVA test with repeated measures and paired sample t test in acquisition phase and Tukey post hoc test were used to analyze data. The results revealed that stress damaged learning and memory (P=0.03). However, physical activity neutralized performance damage caused by stress (P=0.000). Physical activity group showed a significant positive effect on the time to reach the platform in the acquisition phase (P=0.005) and on cognitive function in recall phase (P=0.006) which was a sign of positive effect of physical activity on learning and memory. Therefore according to the present results which show that stress impairs learning and memory, it is expected that physical activity will be used as an effective factor to moderate stress.
Seyyed Amir Ahmad Mozaffari; Leila Sabaghiyanrad; Hojat Hatami
Abstract
The major aim of this study was to compare the effectiveness of two teachingmethods of traditional (common) and integrated for physical education on learningbiology and developing social skills in male junior students. This study was semiexperimentalwhich was conducted in Islamshahr city for 12 weeks. ...
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The major aim of this study was to compare the effectiveness of two teachingmethods of traditional (common) and integrated for physical education on learningbiology and developing social skills in male junior students. This study was semiexperimentalwhich was conducted in Islamshahr city for 12 weeks. The statisticalpopulation consisted of 79 volunteer junior students who studied the second gradeand 52 students were selected by an IQ test and were assigned to two groups oftraditional (n=26) and integrated (n=26) purposively. During these three months,physical education and biology were taught by the common method (separately)for the traditional group while biology was integrated with physical education andtaught for the integrated group. The data were analyzed using Wilcoxon test, UMann Whitney test and t test. The results revealed a significant difference inlearning biology between traditional and integrated groups at α<0.05. The t testresults revealed a significant difference in the mean scores of impulsive behaviorsbetween traditional and integrated groups at α<0.01, that is, the mean scoressignificantly decreased in the integrated method compared to the traditionalmethod. Also, there was a significant difference in the mean scores of suitablesocial behaviors of subjects between integrated and traditional groups (α<0.001).In other words, mean scores of the students in the integrated group significantlyincreased compared to the traditional group.
Mohamad Hossein Zamani; Mahdi Zarghami; Sedigheh Heidarinezhad
Abstract
Feedback is one of the most important variables that affects the performance of motor learning and the way of implementing skills and has an important role in motor control and motor skill acquisition. This study aimed at evaluating the acquisition and retention of new skills in children with autism ...
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Feedback is one of the most important variables that affects the performance of motor learning and the way of implementing skills and has an important role in motor control and motor skill acquisition. This study aimed at evaluating the acquisition and retention of new skills in children with autism in augmented feedbacks with various frequencies. Study method was semi-experimental and study design was pretest–posttest. The retention test was carried out with three feedback groups (0%, 50% and 100%). The study population consisted of 6-8-year-old male children with autism in Ahvaz city. 21 subjects were selected through available and purposive sampling method as the sample of the study and were randomly divided into three groups. The subjects' task was to throw a tennis ball over their shoulders towards a target drawn on the ground. In the acquisition phase, subjects threw 60 tennis balls. Group 0% did not receive any feedback, group 50% received feedback in half of their efforts and group 100% received feedback in all their efforts. 24 hours after the acquisition phase, retention test was performed in 10 trials. After checking the data normality and variance equality, data were analyzed by analysis of variance with repeated measures, ANOVA and Tukey post hoc test. The results showed a significant difference in the acquisition and retention stages among the three groups (P=0.001). Group 100% outperformed both in the acquisition and retention phases. It is generally suggested that in the skill learning process, children with autism benefit from augmented feedback with high frequency.
Ali Seghatoleslami; Mahmood Shaikh; Naser Naghdi; Elahe Arab Ameri; Nabiollah Numvar Asl
Abstract
It is important for people to improve cognitive and motor performance. The purpouse of this study was to investigate the effect of running on treadmill in spatial memory and learning and motor performance. 24 Albino-Wistar healthy male rats were randomly divided into control and activity groups. Activity ...
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It is important for people to improve cognitive and motor performance. The purpouse of this study was to investigate the effect of running on treadmill in spatial memory and learning and motor performance. 24 Albino-Wistar healthy male rats were randomly divided into control and activity groups. Activity group ran 7 days on treadmill (speed 22m/min 30 minutes a day). After the end of activity period, Morris Water Maze and open-field tests were done to respectively assess spatial learning and motor performance. It was used latency time, and distance moved to find platform to assess spatial learning, and distance moved, mobility duration, and movement speed to assess motor activity. It was used SEM±M and analyze variance (2groups*3days) and independent-t tests to analyze data.Results indicated that In spatial learning, activity group was significantly better in acquisition (distance moved F2,44=6/578 p=0/003 and latency time F2,44=10/550, p=0/000 ), probe (time spend in target quarter t22=2/534 , p=0/019), and retrieval tests (distance moved t22=2/651, p-0/015) than control group. In motor activity there was no significant difference between two groups.The results of this study show that the forced running of rats on treadmill for a week can improve learning and memory.
Hasan Mohammadzadeh; Mandana Heydari
Abstract
The aim of this study was to determine the probable relationship of failure and success with self-efficacy expectations in learning shooting skill. The subjects were 63 physical education students of Urmia University who were assigned to two experimental and one control group. The subjects received training ...
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The aim of this study was to determine the probable relationship of failure and success with self-efficacy expectations in learning shooting skill. The subjects were 63 physical education students of Urmia University who were assigned to two experimental and one control group. The subjects received training in air-rifle shooting for one day and practiced it for three days. At the end of each practice session, the first experimental group received verbal feedback regarding their successful performance (high score and low error). The second experimental group received verbal feedback regarding their failure (low score and high error). The control group did not receive any feedback. At the end of final training session and after 48 hours of detraining, the subjects performed the criteria task as performance and retention tests. During the retention phase (before they performed criteria task), the subjects filled out self-efficacy questionnaire of Bandura and Adams (1997). The questionnaire included one open-ended question on the main reason for the subjects’ performance and five other questions on predicting their performance in retention test. Data were analyzed by analysis of variance (ANOVA) test to determine the differences resulted from research variables. Pearson correlation coefficient test was used to determine significant relationships of predicted and the real performance (?=0.05). The findings showed that the control and the failed groups had weaker performance than the successful group. Further analysis indicated that the level and the power of the perceived self-efficacy were significant and higher among the members of the successful group compared to the failed and the control group. In addition, the relationship between predicted performance and the real performance was significant only in the successful group. The findings supported Bandura’s theory regarding the effects of successful experiences on improving self-efficacy.
Shahzad Tahmasbi; Ahmad Farokhi; Naser Naghdi; Fazlolah Bagherzade; Anoushirvan Kazemnejad; Mehdi Shahbazi
Volume 1, Issue 2 , October 2009, , Pages 21-46
Abstract
The purpose of this study was to evaluate the effect of two regimes during rats' gestation and lactation on learning, memory and motor function of their offspring. For this purpose, female rats (Albino-Wistar) were obtained from Pasteur Institute, Iran. After mating, 12 pregnant rats were divided into ...
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The purpose of this study was to evaluate the effect of two regimes during rats' gestation and lactation on learning, memory and motor function of their offspring. For this purpose, female rats (Albino-Wistar) were obtained from Pasteur Institute, Iran. After mating, 12 pregnant rats were divided into three groups and they had their special regimes during their last week of pregnancy as well as their lactation. Control group used a standard diet, the zinc deficient (ZnD) group a diet deficient in zinc and the zinc supplement (ZnS) group a standard diet and enhanced zinc (10ppm) in their drinking water. 12 male offspring in each group were selected as the statistical sample and they were tested for learning and memory in MWM on their 56th natal day (ND) and were tested for motor activity in open-field on their 66th natal day. One-way ANOVA, post hoc Tukey test and repeated measures ANOVA were used to analyze the data (P