نوع مقاله : مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I
نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، دانشکدة علوم انسانی، دانشگاه شاهد، تهران، ایران.
2 گروه تربیت بدنی و علوم ورزشی دانشکده علوم انسانی، دانشگاه شاهد، تهران، ایران.
3 گروه تربیت بدنی و علوم ورزشی، دانشکدة علوم انسانی، دانشگاه شاهد، تهران، ایران .
چکیده
مقدمه: فعالیت ورزشی می تواند عملکرد مغز را تقویت و از آن محافظت می کند. با وجود این یکی از علل اصلی عدم انجام فعالیت ورزشی به مقدار توصیه شده، کمبود زمان است. هدف پژوهش حاضر تعیین تأثیر تمرین تناوبی سرعتی برمقادیر عامل رشد عصبی و یادگیری و حافظۀ فضایی موشهای صحرایی بالغ بود.
روش پژوهش: برای انجام کار 16 سر رت نر بالغ به دو گروه مساوی تقسیم شدند (کنترل و تمرین تناوبی 9 تکرار 10 - سرعتی). پروتکل تمرین تناوبی سرعتی شامل 8 هفته دویدن روی تردمیل بود (سه جلسه در هفته، 4 ثانیه ای با 1 دقیقه استراحت بین تکرارها). در انتهای هفتۀ هشتم، عملکرد شناختی رتها با استفاده از آزمون شاتل بررسی شد. در پایان، رتها بیهوش و هیپوکمپ برداشته شده و مقادیر عامل رشد عصبی سنجیده شد.
یافته ها: یافته ها نشان داد سطوح عامل رشد عصبی هیپوکامپ در گروه تمرین تناوبی سرعتی نسبت به گروه کنترل به طور معناداری بالاتر بود ( 0/001=p).همچنین در گروه تمرین ورزشی عملکرد رتها در آزمون ماز Yو شاتل باکس بهتر از گروه کنترل بود، اما میزان تفاوت از نظر آماری معنادار نبود(0/05<p).
نتیجه گیری: براساس یافته های پژوهش حاضر، به نظر می رسد تمرینات تناوبی سرعتی (با تکرارهای 10 ثانیه ای) می تواند موجب افزایش سطح عامل رشد عصبی هیپوکمپ شود، اگرچه برای بهبود دانش ما در مورد تأثیر آن برعملکرد شناختی به تحقیقات بیشتری نیاز است.
کلیدواژه‌ها
عنوان مقاله [English]
The Effect of Sprint Interval Training on Hippocampal Nerve Growth Factor and Cognitive Performance in Male Wistar Rats
نویسندگان [English]
- Elham Azizi 1
- Esmail Nasiri 2
- Maryam Khalesi 3
1 Department of Physical Education and Sports Sciences, Faculty of Humanities, Shahed University, Tehran, Iran.
2 Department of Physical Education and Sports Sciences, Faculty of Humanities, Shahed University, Tehran,
3 Department of Physical Education and Sports Sciences, Faculty of Humanities, Shahed University, Tehran, Iran .
چکیده [English]
Introduction: Sports activities can protect the brain and improve its function. However, the lack of time is one of the primary reasons for not participating in the recommended amount of sports activities. Therefore, the present study aimed to investigate the effects of sprint interval training (SIT) on hippocampal nerve growth factor (NGF) levels, learning, and spatial memory in adult male rats.
Methods: For this, 16 male Wistar rats were divided into two equal groups (control and SIT). The SIT protocol consisted of eight weeks of running on the treadmill (three sessions per week, 4-9 repetitions of 10 seconds sprints, and 1 min rest between repetitions). At the end of the eighth week, the rats’ cognitive performance was evaluated using the shuttle box and Y-maze avoidance tests. Finally, rats were anesthetized and the hippocampus was removed and NGF levels were measured.
Results: The findings showed that in the SIT group, the hippocampal NGF levels were significantly higher than the control group (p=0.001). Moreover, rats in the SIT group had better performance in the shuttle box and Y-maze avoidance tests than the control group, but the difference between groups was not statistically significant (p>0.05).
Conclusion: Based on the findings of the present study, it seems that SIT (with 10 seconds repetitions) can increase the hippocampal NGF levels, though, to improve our knowledge about its effect on cognitive performance, more studies are needed
کلیدواژه‌ها [English]
- Hippocampus
- Learning
- Memory
- Nerve growth Factor
- Sprint Interval Training
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